rNuQs from Volition are reliable, ready-to-use recombinant nucleosomes that reflect real chromatin biology.
Why choose recombinant nucleosomes from Volition?
Volition’s recombinant nucleosomes offer a robust, reproducible alternative to native chromatin preparations. Assembled using defined recombinant histones under tightly controlled conditions, they deliver the consistency required for reliable epigenetics, chromatin biology, and drug discovery workflows. With off-the-shelf recombinant nucleosome configurations, this portfolio provides one of the most comprehensive commercial nucleosome offerings currently available.
Researchers can select nucleosomes based on histone composition, post-translational modifications (PTMs), and citrullination patterns, with options to tailor key parameters to specific experimental needs.
Unlike many chromatin reagents, Volition nucleosomes are stored and shipped at +4 °C in a glycerol-free buffer, simplifying handling while preserving structural integrity and experimental performance. The range includes precisely defined post-translational modifications (PTMs), engineered citrullination patterns, and exclusive H3K18lactylation nucleosomes not available from other suppliers.
Key features
Consistently high quality, batch to batch
Manufactured in an ISO 13485 certified facility, delivering exceptional reproducibility and quality control not available from other suppliers.
Exclusive H3K18lac nucleosomes
Uniquely available, not offered by other suppliers.
Ready to use. No −80 °C storage required
Supplied in a glycerol-free buffer and stored at +2-8 °C, eliminating the need for ultra-low freezers. This avoids repeated freeze–thaw cycles, helping preserve nucleosome integrity and ensuring consistent experimental performance.
No glycerol, no downstream interference, to use.
Glycerol-free formulation reduces the risk of assay interference in biochemical, biophysical, and enzymatic applications.
Broad panel of recombinant nucleosome variants
20+ distinct nucleosome variants available, enabling flexible experimental design.
Defined citrullination patterns
Precisely engineered nucleosomes with defined citrullination for chromatin biology studies and NET-related studies.
Multiple post-translational modifications on a single nucleosome
Enables investigation of post-translational modification crosstalk in a controlled, biologically relevant context.
Need a specific post-translational modification combination, DNA length, or citrullination pattern?
Volition offers custom nucleosome configurations and bulk supply options to support larger studies and screening workflows.
Contact us to discuss feasibility and lead times.
All nucleosomes are produced and supplied directly by Volition, giving you confidence in quality, traceability, and availability.
Need help choosing the right product or planning your experiment?
Visit our FAQs for quick answers, or reach out to our team for expert support.