r.NuQs from Volition are reliable, ready-to-use recombinant nucleosomes that save time, reduce variability, and reflect real chromatin biology.
Reliable, ready-to-use recombinant nucleosomes designed for reproducible chromatin and epigenetics research. Supplied in a glycerol-free buffer and stored at +4 °C, with defined PTMs, precise citrullination patterns, and custom DNA lengths to closely reflect native chromatin biology.
Key Features
Consistently high quality, batch to batch
Manufactured in an ISO 13485 certified facility, delivering exceptional reproducibility and quality control not available from other suppliers.
Ready to use – no −80 °C storage required
Supplied in a glycerol-free buffer and stored at +4 °C, eliminating the need for ultra-low freezers and simplifying day-to-day handling.
Preserves nucleosome integrity during routine use
+4 °C storage avoids repeated freeze-thaw cycles, helping maintain structural stability and experimental consistency.
No glycerol, no downstream interference
Glycerol-free formulation reduces the risk of assay interference in biochemical, biophysical, and enzymatic applications.
Broad panel of recombinant nucleosome variants
26 distinct nucleosome variants available, enabling flexible experimental design.
Defined citrullination patterns
Precisely engineered citrullination for reproducible NET formation and chromatin biology studies.
Multiple PTMs on a single nucleosome
Enables investigation of PTM crosstalk in a controlled, biologically relevant context.
Exclusive H3K18lac nucleosomes
Uniquely available – not offered by other suppliers.
Why Buy Recombinant Nucleosomes from Volition?
Volition’s recombinant nucleosomes offer a robust, reproducible alternative to native chromatin preparations. Assembled using defined recombinant histones under tightly controlled conditions, they deliver the consistency required for reliable epigenetics, chromatin biology, and drug discovery workflows.
With 26 off-the-shelf recombinant nucleosome configurations (and up to 74 potential variants), this portfolio provides one of the most comprehensive commercial nucleosome offerings currently available. Researchers can select nucleosomes based on histone composition, PTMs, citrullination patterns, and DNA length, with options to tailor key parameters to specific experimental needs.
Unlike many chromatin reagents, Volition nucleosomes are stored and shipped at +4 °C in a glycerol-free buffer, simplifying handling while preserving structural integrity and experimental performance. The range includes precisely defined PTMs, engineered citrullination patterns, and exclusive H3K18lac nucleosomes not available from other suppliers.
Custom options & bulk orders
Need a specific PTM combination, DNA length, or citrullination pattern?
Volition offers custom nucleosome configurations and bulk supply options to support larger studies and screening workflows.
Contact us to discuss feasibility and lead times.
FAQs & support
All nucleosomes are manufactured and supplied directly by Volition, ensuring quality, traceability, and continuity of supply.
Technical support is available to help with product selection, experimental design, and application-specific questions.